| 摘要 |
The invention provides isolated nucleic acids molecules, designated 53014 nucleic acid molecules, which encode novel metalloprotease family members. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing 53014 nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a 53014 gene has been introduced or disrupted. The invention still further provides isolated 53014 proteins, fusion proteins, antigenic peptides and anti-53014 antibodies. Diagnostic and therapeutic methods utilizing compositions of the invention are also provided.
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