发明名称 2-THIO-SUBSTITUTED IMIDAZOLE DERIVATIVES AND THE USE THEREOF IN THE PHARMACEUTICAL INDUSTRY
摘要 The invention relates to 2-thio-substituted imidazole derivatives of formula I, wherein the groups R1, R2, R3 and R4 are defined as per the description. The inventive compounds have an immunomodulating action and/or an inhibitive action on the release of cytokine and are therefore suitable for treating diseases, which are related to the dysfunction of the immune system.
申请公布号 WO02066458(A2) 申请公布日期 2002.08.29
申请号 WO2002EP01746 申请日期 2002.02.19
申请人 MERCKLE GMBH;LAUFER, STEFAN;KOTSCHENREUTHER, DUNJA;MERCKLE, PHILIPP;TOLLMANN, KAROLA;STRIEGEL, HANS-GUENTER 发明人 LAUFER, STEFAN;KOTSCHENREUTHER, DUNJA;MERCKLE, PHILIPP;TOLLMANN, KAROLA;STRIEGEL, HANS-GUENTER
分类号 A61K31/164;A61K31/4164;A61K31/4439;A61K31/4545;A61K31/5377;A61P1/02;A61P1/04;A61P1/16;A61P1/18;A61P3/10;A61P9/00;A61P9/10;A61P11/00;A61P17/06;A61P17/14;A61P19/06;A61P19/10;A61P25/00;A61P25/08;A61P25/28;A61P29/00;A61P31/04;A61P31/12;A61P31/18;A61P35/00;A61P37/00;A61P37/02;A61P37/06;A61P37/08;A61P43/00;C07D401/04;C07D401/14 主分类号 A61K31/164
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