发明名称 |
2-THIO-SUBSTITUTED IMIDAZOLE DERIVATIVES AND THE USE THEREOF IN THE PHARMACEUTICAL INDUSTRY |
摘要 |
The invention relates to 2-thio-substituted imidazole derivatives of formula I, wherein the groups R1, R2, R3 and R4 are defined as per the description. The inventive compounds have an immunomodulating action and/or an inhibitive action on the release of cytokine and are therefore suitable for treating diseases, which are related to the dysfunction of the immune system. |
申请公布号 |
WO02066458(A2) |
申请公布日期 |
2002.08.29 |
申请号 |
WO2002EP01746 |
申请日期 |
2002.02.19 |
申请人 |
MERCKLE GMBH;LAUFER, STEFAN;KOTSCHENREUTHER, DUNJA;MERCKLE, PHILIPP;TOLLMANN, KAROLA;STRIEGEL, HANS-GUENTER |
发明人 |
LAUFER, STEFAN;KOTSCHENREUTHER, DUNJA;MERCKLE, PHILIPP;TOLLMANN, KAROLA;STRIEGEL, HANS-GUENTER |
分类号 |
A61K31/164;A61K31/4164;A61K31/4439;A61K31/4545;A61K31/5377;A61P1/02;A61P1/04;A61P1/16;A61P1/18;A61P3/10;A61P9/00;A61P9/10;A61P11/00;A61P17/06;A61P17/14;A61P19/06;A61P19/10;A61P25/00;A61P25/08;A61P25/28;A61P29/00;A61P31/04;A61P31/12;A61P31/18;A61P35/00;A61P37/00;A61P37/02;A61P37/06;A61P37/08;A61P43/00;C07D401/04;C07D401/14 |
主分类号 |
A61K31/164 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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