发明名称 Chromenone and chromanone derivatives as integrin inhibitors.
摘要 The invention relates to compounds having formula (I), wherein R<1>, R<2>, R<3>, R<4>, R<5>, R<7>, R<8>, R<11>, Z, m and n have the meaning cited in claim 1, and to the physiologically acceptable salts and solvates which can be used as integrin inhibitors, especially in the prophylaxis and treatment of circulatory diseases, in case of thrombosis, myocardial infarction, coronary heart diseases, arteriosclerosis, osteoporosis, pathologic processes caused or propagated by angiogenesis and in tumor therapy.
申请公布号 ZA200104411(B) 申请公布日期 2002.08.29
申请号 ZA20010004411 申请日期 2001.05.29
申请人 MERCK PATENT GMBH. 发明人 CLAUS FITTSCHEN;JOACHIM MAERZ;MATTHIAS WIESNER;SIMON GOODMAN;PETER RADDATZ
分类号 A61K31/352;A61K31/4178;A61K31/4184;A61K31/4427;A61K31/443;A61P7/02;A61P9/00;A61P9/10;A61P19/00;A61P19/10;A61P21/00;A61P29/00;A61P35/00;A61P43/00;C07D233/66;C07D311/22;C07D311/24;C07D405/12 主分类号 A61K31/352
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