| 摘要 |
<p>An improved liquid handling machine (9) capable of regulating the temperature of assay compounds in the automated preparation of culture trays for biological assays is disclosed. The machine includes a horizontally movable table (10) positioned beneath a vertically movable head (12). The table (10) is divided into a plurality of stations holding mixing trays, culture trays and reservoirs of liquid assay compound. The head (12) holds a plurality of pipettes (36) which aspirate and expel liquid to transfer and mix the assay compounds between the reservoir, the mixing trays and the culture trays upon coordinated movement of the head and the table as controlled by a microprocessor. Each station on the table has independent heating, cooling and temperature sensing elements (120) for regulating the temperature of the liquid held in a tray or reservoir at the station. A device for automatically evaluating the results of the assay, such as by fluorescence, spectrophotometric or radioactive techniques is incorporated with the improved liquid handling machine.</p> |
