发明名称 |
Pharmaceutical compositions comprising cross-linked polymers loaded with drugs prepared by using supercritical fluids to solubilize and load the drugs on to the polymers |
摘要 |
Pharmaceutical compositions in powder form are prepared by loading drugs solubilized in supercritical fluids on cross-linked polymers. The loading process is carried out by means of two steps. In the first step the supercritical fluid is saturated with the drug in suitable temperature and pressure conditions. In the second step the supercritical fluid containing the drug is contacted with the cross-linked polymer. Owing to its particular properties the supercritical fluid penetrates into the polymer and allows the drug to impregnate the polymer itself. After the removal of the fluid the drug remains in the polymer itself.
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申请公布号 |
NZ505290(A) |
申请公布日期 |
2002.08.28 |
申请号 |
NZ19980505290 |
申请日期 |
1998.11.16 |
申请人 |
EURAND INTERNATIONAL S |
发明人 |
CARLI, FABIO;COLOMBO, ITALO;ALESSI, PAOLO;KIKIC, IRENEO;CORTESI, ANGELO |
分类号 |
A61K9/14;A61K9/16;A61K47/30;(IPC1-7):A61K9/16;A61K31/14 |
主分类号 |
A61K9/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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