发明名称 USE OF ESTERS OF L-CARNITINE OR ALKANOYL L-CARNITINES AS CATIONIC LIPIDS FOR THE INTRACELLULAR DELIVERY OF PHARMACOLOGICALLY ACTIVE COMPOUNDS
摘要 The use of esters of L-carnitine and alkanoyl L-carnitines as cationic lipids for the intracellular delivery of pharmacologically active compounds is described. The esters according to the invention have general formula (II) <CHEM> wherein the R groups are as defined in the description.
申请公布号 HU0201446(A2) 申请公布日期 2002.08.28
申请号 HU20020001446 申请日期 2000.04.11
申请人 SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. 发明人 CRITELLI LUCIANA;PISANO CLAUDIO;SALVATORI GIOVANNI;SANTANIELLO MOSE;TINTI MARIA ORNELLA
分类号 A61K8/00;A61K8/11;A61K8/14;A61K8/30;A61K8/37;A61K8/44;A61K9/127;A61K31/225;A61K31/337;A61K31/4745;A61K39/00;A61K45/00;A61K47/18;A61K47/24;A61K47/44;A61K48/00;A61P35/00;A61Q19/00;C07C229/02;C07C229/22 主分类号 A61K8/00
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