| 发明名称 |
A process for the preparation of midodrine |
| 摘要 |
<p>The invention provides a process for the preparation of 2-amino-N-Ä2-(2,5-dimethoxyphenyl)-2-hydroxyethylÜacetamide of the formula 1 by hydrogenolysis of substituted 2-dibenzylamino-N-Ä2-(2',5'-dimethoxyphenyl)-2-hydroxy-ethylÜacetamide having the formula (5), wherein Ar and Ar' are aryl groups. <CHEM> <CHEM></p> |
| 申请公布号 |
EP1234817(A1) |
申请公布日期 |
2002.08.28 |
| 申请号 |
EP20020002042 |
申请日期 |
2002.02.07 |
| 申请人 |
CHEMAGIS LTD. |
发明人 |
BRAND, MICHAEL;CHEN, RONIT;YIGAL, DEBY;KASPI, JOSEPH |
| 分类号 |
C07B61/00;C07C231/12;C07C237/08;(IPC1-7):C07C237/08 |
主分类号 |
C07B61/00 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
