发明名称 Palatable oral coenzyme Q liquid
摘要 The present invention relates to a composition in pharmaceutical dosage form of coenzyme Q or ubiquinol which can be administered to children in an oral dosage form as a pleasant-tasting liquid. The dosage form comprises an effective amount of coenzyme Q or ubiquinol ranging from about 0.05% to about 10%, more preferably about 1% to about 7.5% by weight of the composition in combination with a minor amount of a polysorbate surfactant such as a Tween(TM) surfactant, most preferably, polysorbate 80, a major amount of a vegetable oil or triglyceride, in further combination with an amount of phospholipid such as hydroxylated lecithin effective to maintain ubiquinone/ubiquionol in hydrosoluble form and to substantially enhance the palatability of ubiquinone or ubiquinol in combination with a sweetener solution as well as an amount of water preferably ranging from about 5% to about 45% by weight.
申请公布号 US6441050(B1) 申请公布日期 2002.08.27
申请号 US20000650487 申请日期 2000.08.29
申请人 CHOPRA RAJ K. 发明人 CHOPRA RAJ K.
分类号 A61K9/00;A61K31/122;(IPC1-7):A61K31/12;A01N31/14;A61K31/075;A61K47/00 主分类号 A61K9/00
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