BPN' variants having decreased adsorption and increased hydrolysis

摘要

The present invention relates to subtilisin BPN' variants comprising at least one or more amino acid positions having a different amino acid than that occurring in wild-type subtilisin BPN' (i.e., substitution) at specifically identified positions, whereby the BPN' variant has decreased adsorption to, and increased hydrolysis of, an insoluble substrate as compared to wild-type subtilisin BPN'. The present invention further relates to various cleaning compositions comprising such BPN' variants.