发明名称 |
Antibodies to argatroban derivatives and their use in therapeutic and diagnostic treatments |
摘要 |
Antibodies to a therapeutic agent and its derivatives and conjugates are disclosed, including antibodies to argatroban and its derivatives and conjugates. The antibodies are useful as reagents in assays and diagnostic kits for determining the concentration of a therapeutic agent or its derivatives and conjugates in biological samples, and further have therapeutic uses in treatment for potential toxicity associated with stable therapeutic conjugates and derivatives, both in vivo and ex vivo.
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申请公布号 |
US6440417(B1) |
申请公布日期 |
2002.08.27 |
申请号 |
US19990434605 |
申请日期 |
1999.11.05 |
申请人 |
CONJUCHEM, INC. |
发明人 |
THIBAUDEAU KAREN;BLANCHARD DOMINIQUE;BRIDON DOMINIQUE P.;EZRIN ALAN M.;HARDY MARGARET;BOUDJELLAB NISSAB |
分类号 |
A61P7/02;C07K16/44;(IPC1-7):C07K16/44;A61K39/395;A61K39/44;C07H19/00 |
主分类号 |
A61P7/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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