发明名称 A PROCESS FOR THE PREPARATION OF MIDODRINE
摘要 The invention provides a process for the preparation of 2-amino- N-[2-(2,5-dimethoxyphenyl)- 2-hydroxyethyl]acetamide of the formula 1 b y hydrogenolysis of substituted 2-dibenzylamino-N-[2-(2',5'-dimethoxyphenyl)- 2-hydroxy-ethyl]acetamide having the formula (5), wherein Ar and Ar1 are ary l groups. (See fig I and II)
申请公布号 CA2366311(A1) 申请公布日期 2002.08.26
申请号 CA20012366311 申请日期 2001.12.31
申请人 CHEMAGIS LTD. 发明人 CHEN, RONIT;YIGAL, DEBY;KASPI, JOSEPH;BRAND, MICHAEL
分类号 C07B61/00;C07C231/12;C07C237/08;(IPC1-7):C07C233/19;C07C231/08 主分类号 C07B61/00
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