FORMULATION FOR DELIVERY OF INSULIN AND PREPARATION METHOD THEREOF

摘要

The present invention relates to a liquid insulin formulation and the preparation method thereof. More particularly, the present invention relates to a liquid and powder formulations comprising a monoglyceride, an emulsifier, organic solvent, insulin and acidic aqueous solution. The present invention relates to the liquid and powder insulin formulations with a higher encapsulation efficiency of insulin, higher bioavailability upon oral administration with higher patient compliance and the preparation method thereof.