SCREENING METHODS AND AGENTS

摘要

The present invention relates to a method for screening for agents which modulate the binding of p53 to p300, and agents identified using such an assay. Such agents include peptide mimetics of regions of p53 and/or p300 which have been identified as contact region for the other protein. The agents of the present invention are candidates for use in the treatment of, for example cancer, or ischemia.