PROCESS FOR PRODUCING 4-TRIFLUOROMETHOXYBENZYL HALIDE COMPOUND

摘要

A process for producing a 4-trifluoromethoxybenzyl halide compound represented by the following formula (4) (4) (wherein R<1> represents hydrogen or alkyl; and X represents a halogen atom derived from the halogenating agent to be used), characterized by reacting trifluoromethoxybenzene, which is represented by the following formula (1), (1) with at least one compound selected among aldehyde compounds represented by the following formula (2) R<1>CHO (2) (wherein R<1> is the same as defined above), acetal compounds represented by the following formula (3) (3) (wherein R<1> is the same as defined above; and R<2> and R<3> may be the same or different and each represents alkyl), paraformaldehyde, and 1,3,5-trioxane in the presence of an acid catalyst and a halogenating agent and of a phase-transfer catalyst.