摘要 |
A class of 2-aryloxy-2-arylalkanoic acids comprises compounds that are potent agonists of PPAR alpha and/or gamma, and are therefore useful in the treatment, control or prevention of non-insulin dependent diabetes mellitus (NIDDM), hyperglycemia, dyslipidemia, hyperlipidemia, hypercholesterolemia, hypertriglyceridemia, atherosclerosis, obesity, vascular restenosis, inflammation, and other PPAR alpha and/or gamma mediated diseases, disorders and conditions. |
申请人 |
MERCK & CO., INC.;ADAMS, ALAN, D.;JONES, A., BRIAN;BERGER, JOEL, P.;DROPINSKI, JAMES, F.;ELBRECHT, ALEXANDER;LIU, KUN;MACNAUL, KAREN LAMB;SHI, GUO-QIANG;VON LANGEN, DEREK, J.;ZHOU, GAOCHAO |
发明人 |
ADAMS, ALAN, D.;JONES, A., BRIAN;BERGER, JOEL, P.;DROPINSKI, JAMES, F.;ELBRECHT, ALEXANDER;LIU, KUN;MACNAUL, KAREN LAMB;SHI, GUO-QIANG;VON LANGEN, DEREK, J.;ZHOU, GAOCHAO |