METHODS AND COMPOSITIONS FOR THE MANUFACTURE OF HIGHLY POTENT ANTHRACYCLINE-BASED ANTITUMOR AGENTS
摘要
The present invention discloses new and novel substituted anthracyclines having a three ring system or other DNA binding moities. These congeners show high activity in vitro against several tumor cell lines. The invention also describes anthracycline-based DNA alkylators.
申请公布号
WO0026223(A9)
申请公布日期
2002.08.22
申请号
WO1999US25672
申请日期
1999.11.02
申请人
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM;PRIEBE, WALDEMAR;PRZEWLOKA, TERESA;FOKT, IZABELA;LING, YI-HE;PEREZ-SOLER, ROMAN
发明人
PRIEBE, WALDEMAR;PRZEWLOKA, TERESA;FOKT, IZABELA;LING, YI-HE;PEREZ-SOLER, ROMAN