| 摘要 |
Compounds of the invention are useful in inhibiting thrombin and associated thrombotic occlusions having the following structure Formula (I): wherein u is CH or N; Q is 1)-N(R<25>)CH(R<30>)- wherein the nitrogen atom is attached to R<1>, and R<25> and R<30> are independently selected from the group consisting of hydrogen, C3-6cycloalkyl, and C1-6alkyl, or 2) wherein the nitrogen atom is attached to R<1>, and m is 0, 1, or 2. |
| 申请人 |
MERCK & CO., INC.;SELNICK, HAROLD, G.;YOUNG, MARY BETH;NANTERMET, PHILIPPE, G.;BARROW, JAMES, C.;WILLIAMS, PETER, D.;LYLE, TERRY, A.;STAAS, DONNETTE, D.;STAUFFER, KENNETH, J.;SANDERSON, PHILIP, E. |
发明人 |
SELNICK, HAROLD, G.;YOUNG, MARY BETH;NANTERMET, PHILIPPE, G.;BARROW, JAMES, C.;WILLIAMS, PETER, D.;LYLE, TERRY, A.;STAAS, DONNETTE, D.;STAUFFER, KENNETH, J.;SANDERSON, PHILIP, E. |
