摘要 |
This invention relates to a method of treating ischemic or diseased myocardi um by injecting a therapeutic agent, such as a gene, protein, cell or drug, int o normal myocardium, preferably adjacent to an ischemic zone in the heart of a subject. The method is useful for inducing angiogenesis and collateral blood vessel formation to improve cardiac function in subjects with ischemic heart disease. The method can also be used to promote tissue regeneration in such subjects.
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