| 发明名称 |
PEPTIDE IN GRADO DI INIBIRE L'ATTIVITA' DEL FATTORE DI CRESCITA DERIVATO DALLE PIASTRINE (PDGF-BB) E DEL FATTORE DI CRESCITA DERIVATO DAI FI |
| 摘要 |
A novel peptide, derived from the human fibroblast growth factor (bFGF), is identified. The molecule is able to inhibit in vitro the effects of Platelet Derived Growth Factor (PDGF-BB) and basic Fibroblast Growth Factor (bFGF) on primary rat smooth muscle cells (RASMC) and primary bovine endothelial cells (BAEC) The molecule is also able to inhibit in vivo angiogenesis CD1 mice. |
| 申请公布号 |
ITRM20010088(A1) |
申请公布日期 |
2002.08.21 |
| 申请号 |
IT2001RM00088 |
申请日期 |
2001.02.21 |
| 申请人 |
PROVINCIA ITALIANA DELLA CONGREGAZI ONE DEI FIGLI DELL'IMMACOLATA CONCE |
发明人 |
FACCHIANO ANTONIO;FACCHIANO FRANCESCO;FACCHIANO ANGELO |
| 分类号 |
A61K38/00;A61P7/02;A61P9/00;A61P35/00;A61P35/04;C07K7/06;C07K14/50 |
主分类号 |
A61K38/00 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
