| 摘要 |
Essentially protein-free O-carbohydrate or O-polysaccharide antigens are separated from a species, or serogroup of a species, of bacteria of the genus Legionella, and coupled to an activated chromatographic column. The column so prepared is used to purify raw antibodies to the same species or serogroup of a species, of Legionella. The resulting antigen-specific antibodies are used in immunochemical assays for detecting Legionnaires disease, Pontiac fever and other Legionella-caused diseases in humans and for detecting Legionella bacteria in environmental samples. A rapid, highly specific and sensitive immunoassay for Legionella pneumophila serogroup 1 conducted in an immunochromatographic test device is described in detail. |
