| 摘要 |
The present invention provides an adenoviral vector encoding an anti-apoptotic Bcl-2 gene for cytoprotection, gene therapy, and cellular and organ transplantation. Also provided are various methods of using said adenoviral vector to protect cells for cellular transplantation, or organs for both allotransplantation and xenotransplantation, to improve organ preservation for transplantation, to reduce ischemial/reperfusion injury, to protect endothelial cells from various inducers of injury, and to prolong transgene expression.
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