发明名称 T CELL RECEPTOR PEPTIDES AS THERAPEUTICS FOR IMMUNE-RELATED DISEASE
摘要 Peptides and pharmaceutical compositions comprising immunogenic peptides of a marker T cell receptor (TCR) character- istic of an immune-related disease, capable of preventing, suppressing, or treating the disease, are disclosed. In a preferred em- bodiment, the amino acid sequence of the peptide corresponds to at least par t of a complementarily determining region (CDR) or a hypervariable region of the TCR. Antibodies and/or T cells immunologically reactive to the TCR peptide capable of preven- ting, suppressing, or treating an immune-related disease by passive transfer are also disclosed.
申请公布号 CA2110055(C) 申请公布日期 2002.08.20
申请号 CA19922110055 申请日期 1992.06.01
申请人 XOMA CORPORATION 发明人 VANDENBARK, ARTHUR A.
分类号 A61K38/00;A61K39/00;A61K39/395;A61P29/00;A61P35/00;A61P37/06;A61P43/00;C07K7/08;C07K14/705;C07K14/725;C07K16/00;C07K16/28;C12P21/08;(IPC1-7):C07K14/725;C07K17/02;A61K38/04;C07K7/04;A61K38/17;A61K47/48 主分类号 A61K38/00
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