| 发明名称 |
Peptido-mimetic compounds containing RGD sequence useful as integrin inhibitors |
| 摘要 |
The present invention discloses compounds of formula (I)wherein n is the number 0, 1 or 2. There are also disclosed processes for the preparation of the compounds, together with methods for treating pathologies related to an altered alphavbeta3 integrin-mediated cell attachment, in particular wherein the inhibition of angiogenesis is desired, for example in tumors, also associated with metastasis.
|
| 申请公布号 |
US6437094(B2) |
申请公布日期 |
2002.08.20 |
| 申请号 |
US20010754216 |
申请日期 |
2001.01.05 |
| 申请人 |
SIGMA-TSU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. |
发明人 |
SCOLASTICO CARLO;GIANNINI GIUSEPPE |
| 分类号 |
A61K38/00;A61P13/12;A61P19/10;A61P27/02;A61P35/00;A61P35/04;A61P43/00;C07B53/00;C07B61/00;C07K5/00;C07K5/078;C07K5/093;C07K7/64;(IPC1-7):C07K7/64 |
主分类号 |
A61K38/00 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
