| 摘要 |
-42- Matrix metalloproteinase inhibitors are tricyclicsulfonamides of the Formula I or a pharmaceutically acceptable salt thereof, wherein R1 and R2 include hydrogen, alkyl, and substituted alkyl; R3 is OH o r NHOH; X is O or S(O)n; n is 0, 1, or 2; p is 0, 1, 2, or 3; ~ is absent or a bond; and the sulfur atom bearing (0)q is bonded to the benzo ring at position a o r position b.
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