| 摘要 |
PROBLEM TO BE SOLVED: To provide a method for producing acylpyridines expressed by the formula (3) in a high yield by reacting pyridine carboxylic acids expressed by the formula (1) [wherein, R1 is an alkyl or an aralkyl; (m) is 1-5 integer; and (n) is 0-4 integer, provided that 5>=(m+n)] with carboxylic acids expressed by the formula (2) (wherein, R2, R3 and R4 are the same or different and each H, an alkyl or an aralkyl). SOLUTION: This method for producing the acylpyridine is provided by using a metal oxide catalyst having ammonia-adsorbing points exhibiting <300μmol/(g catalyst) amount of eliminated ammonia in a temperature range between 100 deg.C-800 deg.C when ammonia is adsorbed to the catalyst and then the adsorbed ammonia is eliminated by heating.
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