发明名称 METHOD FOR DETECTING MUTATION IN NUCLEIC ACID SEQUENCE
摘要 PROBLEM TO BE SOLVED: To provide a method capable of examining a number of specimens effectively regarding the presence of the mutation in nucleic acid sequence while suppressing the possibility of making mistake in the judgment to an extremely low level. SOLUTION: The method is carried out by a reaction using a nucleic acid synthetase having 3',5'-exonuclease activity or a mixture of a 3',5'-exonuclease and a nucleic acid synthetase, and an oligonucleotide primer whose 3'-terminal side is modified for inhibiting a nucleic acid reaction.
申请公布号 JP2002223799(A) 申请公布日期 2002.08.13
申请号 JP20010025352 申请日期 2001.02.01
申请人 SHIMADZU CORP 发明人 KOJIMA KOICHI
分类号 C12N15/09;C12Q1/68 主分类号 C12N15/09
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