发明名称 Method of prevention of prostatic carcinoma with 17beta-N-monosubstituted-carbamoyl-4-aza-5alpha-androst-1-en-3-ones
摘要 17beta-N-monosubstituted-carbamoyl-4-aza-5alpha-androst-1-en-3-ones of the formulawherein R1 is selected from hydrogen, methyl and ethyl and R2 is a straight or branched chain alkyl, cycloalkyl, aralkyl of from 1-12 carbons, or monocyclic aryl optionally containing 1 or more lower alkyl substituents of 1-2 carbon atoms and/or 1 or more halogens, and R', R'', R''' are hydrogen or methyl are useful for the prevention of prostatic carcinoma.
申请公布号 US6432971(B2) 申请公布日期 2002.08.13
申请号 US20010875381 申请日期 2001.06.06
申请人 MERCK & CO., INC. 发明人 GORMLEY GLENN J.;STONER ELIZABETH
分类号 A61K31/58;A61P35/00;C07J73/00;(IPC1-7):A61K31/44 主分类号 A61K31/58
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