发明名称 |
Recombinant envelope vaccine against flavivirus infection |
摘要 |
A vaccine contains at least one Drosophila cell-secreted, recombinantly-produced form of a truncated Flavivirus envelope glycoprotein, as an active ingredient, and an adjuvant, as a critical component of the vaccine. The adjuvant is an immunomodulating agent having an iscom-like structure and comprising within the iscom-like structure at least one lipid and at least one saponin, and a pharmaceutically acceptable vehicle. Such a vaccine protects a subject against infection by a Flavivirus.
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申请公布号 |
US6432411(B1) |
申请公布日期 |
2002.08.13 |
申请号 |
US19990352387 |
申请日期 |
1999.07.13 |
申请人 |
HAWAII BIOTECHNOLOGY GROUP |
发明人 |
IVY JOHN;BIGNAMI GARY;MCDONELL MICHAEL;CLEMENTS DAVID E.;COLLER BETH-ANN G. |
分类号 |
A61K39/12;A61P31/12;A61P31/14;(IPC1-7):A61K39/12 |
主分类号 |
A61K39/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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