Film coated microbeads containing active compounds and method of making the same

摘要

Disclosed is a composition for use in dermal application. The composition includes microbeads or chemically stable particles having an internal structure of pores. A chemical compound having a pharmaceutical or cosmetic activity is retained in the internal structure of the porous particles. Each of the particles is coated with at least one of a silicone and a polysiloxane-based compound. Also disclosed is a method of making a composition. A plurality of particles containing a chemical compound in its internal structure is prepared. A coating mixture including at least one of a silicone and a polysiloxane-based compound with a solvent is also prepared. The particles are mixed with the coating mixture, which coats over the particles. The coated particles are subject to drying to evaporate the solvent from the coating mixture.