发明名称 POLYMORPHS OF N METHYL N (3 LCUB;3 [2 THIENYLCARBONYL] PYRAZOL [1 ,5 AGR;] PYRIMIDIN 7 YLRCUB;PHENYL)ACETAMIDE AND COMPOSITIONS AND METHODS RELATED THERETO.
摘要 <p>Polymorphs of N methyl N (3 lcub;3 [2 thienylcarbonyl] pyrazol [1 ,5 agr;] pyrimidin 7 ylrcub;phenyl)acetamide (Compound (1)), and use of the same as a sedative hypnotic, anxiolytic, anticonvulsant, and skeletal muscle relaxant agent. Processes for making the same, as well as related compositions and methods are also disclosed, particularly with regard to treatment of insomnia. A polymorph Form I possessing exception physical and heat stability is provided. A polymorph Form II.</p>
申请公布号 MXPA02002314(A) 申请公布日期 2002.08.12
申请号 MX2002PA02314 申请日期 2000.09.01
申请人 NEUROCRINE BIOSCEINCES, INC. 发明人 WILLIAM J. THIELE
分类号 A61K9/20;A61K9/48;A61K31/505;A61K31/519;A61P21/02;A61P25/08;A61P25/20;A61P25/22;C07D487/02;C07D487/04;(IPC1-7):A61K31/519 主分类号 A61K9/20
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