摘要 |
<p>Polymorphs of N methyl N (3 lcub;3 [2 thienylcarbonyl] pyrazol [1 ,5 agr;] pyrimidin 7 ylrcub;phenyl)acetamide (Compound (1)), and use of the same as a sedative hypnotic, anxiolytic, anticonvulsant, and skeletal muscle relaxant agent. Processes for making the same, as well as related compositions and methods are also disclosed, particularly with regard to treatment of insomnia. A polymorph Form I possessing exception physical and heat stability is provided. A polymorph Form II.</p> |