发明名称 METHODS OF TREATING NUCLEAR FACTOR-KAPPA B MEDIATED DISEASESAND DISORDERS
摘要 The present invention provides a method of treating a disease or a disord er responsive to inhibition of nuclear factor-kB transcription factors comprisi ng administering to a patient in need thereof a sulfonylaminocarbonyl derivativ e, or a pharmaceutically acceptable salt thereof. The methods of the present inventi on are useful for treating, for example, rheumatoid arthritis, osteoarthritis, an autoimmune disease, psoriasis, asthma, a cardiovascular disease, an acute coronary syndrome, congestive heart failure, Alzheimer's disease, multiple sclerosis, cancer, type II diabetes, metabolic syndrome X, or inflammatory bowel disease.
申请公布号 CA2369967(A1) 申请公布日期 2002.08.12
申请号 CA20022369967 申请日期 2002.02.01
申请人 WARNER-LAMBERT COMPANY 发明人 KARATHANASIS, SOTIRIOS KONSTANTINOU;CORNICELLI, JOSEPH ANTHONY
分类号 A61K31/341;A61K31/18;A61K31/255;A61K31/27;A61K31/357;A61K31/381;A61K31/40;A61K31/404;A61K31/4406;A61K31/445;A61K31/5375;A61K31/64;A61P1/00;A61P3/00;A61P3/10;A61P5/50;A61P7/06;A61P9/04;A61P9/10;A61P11/06;A61P17/00;A61P17/06;A61P19/02;A61P21/00;A61P21/04;A61P25/00;A61P25/28;A61P29/00;A61P35/00;A61P37/02;A61P43/00;(IPC1-7):C07C311/53;C07C271/02;C07C307/06 主分类号 A61K31/341
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