NOVEL BIOACTIVE SUBSTANCE

摘要

Novel physiologically active substances having an antitumor activity, a process for producing the same and medicinal use thereof are provided. Namel y, 12-membered ring macrolide compounds represented by the following general formula which are obtained by culture media of Streptomyces sp. Mer-11107 or its variants, pharmacologically acceptable salts thereof or hydrates of the same and a process for producing the same.