TRIARYL COMPOUNDS AND UTILIZATION THEREOF

摘要

Compounds represented by the following general formula (I) or pharmaceutically acceptable salts thereof which have an effect of potentiating the expression of LDL receptor gene and are useful in treating hyperlipemia: (I) wherein a, b and c independently represent each C-H or N; R<1>s independently represent each hydroxy, halogeno, etc.; m is from 0 to 3; D represents 1,3-phenylenediyl, etc.; Y represents an optionally represented benzene ring or a heterocycle; and Z represents -CONR<2>S(O)nR<3>, etc. (wherein n is 1 or 2; R<2> represents H or optionally substituted alkyl; and R<3> represents optionally substituted alkyl, phenyl, etc.); and LDL receptor gene expression potentiating agents containing these compounds as the active ingredient.