NOVEL ANTIVIRAL ACTIVITIES OF PRIMATE THETA DEFENSINS AND MAMMALIAN CATHELICIDINS
摘要
The present invention relates to the use of anti-viral peptides in the inhibition and treatment of viral infections, in particular infections caused by enveloped viruses. These anti-viral peptides, some natural and others artificial, adopt either amphiphilic alpha-helical or a theta structure where the homodimeric or heterodimer peptides are joined by both cysteine bonds and circularization of the peptides. These agents may be used alone or in combination with more traditional anti-viral pharmaceuticals.
申请公布号
WO02060468(A2)
申请公布日期
2002.08.08
申请号
WO2002US02435
申请日期
2002.01.29
申请人
UNIVERSITY OF IOWA RESEARCH FOUNDATION;MAURY, WENDY;STAPLETON, JACK;STINSKI, MARK;ROLLER, RICHARD;MCCRAY, PAUL, B.;TACK, BRIAN
发明人
MAURY, WENDY;STAPLETON, JACK;STINSKI, MARK;ROLLER, RICHARD;MCCRAY, PAUL, B.;TACK, BRIAN