发明名称 |
IMIDAZOLE DERIVATIVES |
摘要 |
The invention related to compounds of the general formula (I), wherein the substituents are defined in claim 1. These compounds have a good affinity to the NMDA (N-methyl-D-aspartate)-receptor subtype selective blockers, which have a key function in modulating neuronal activity and plasticity which mak es them key players in mediating processes underlying development of CNS as wel l as learning and memory formation. These compounds are therefore suitable in the control or treatment of diseases, related to this receptor.
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申请公布号 |
CA2434813(A1) |
申请公布日期 |
2002.08.08 |
申请号 |
CA20022434813 |
申请日期 |
2002.01.21 |
申请人 |
F. HOFFMANN-LA ROCHE AG |
发明人 |
BUETTELMANN, BERND;ALANINE, ALEXANDER;HEITZ NEIDHART, MARIE-PAULE;PINARD, EMMANUEL;WYLER, RENE;JAESCHKE, GEORG |
分类号 |
C07D233/64;A61K31/4164;A61K31/4178;A61K31/4184;A61K31/4439;A61K31/4709;A61K31/4725;A61P25/00;A61P25/04;A61P25/14;A61P25/16;A61P25/24;A61P25/28;A61P31/04;A61P31/12;A61P43/00;C07D233/54;C07D233/61;C07D233/84;C07D233/88;C07D249/08;C07D401/06;C07D401/14;C07D403/06;C07D405/14;C07D521/00;(IPC1-7):C07D233/54;A61K31/416 |
主分类号 |
C07D233/64 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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