| 摘要 |
<p>A method of preserving bodily protein stores such as skeletal muscle mass in a catabolic patient comprises the concomitant administration of (a) α-ketoglutarate (α-KG) and/or α-ketoglutaric acid (α-KGA) and (b) ammonium in amounts effective to preserve skeletal muscle. Also disclosed is the combination of a first pharmaceutical composition comprising α-KG and/or α-KGA in a pharmaceutically acceptable carrier and a second pharmaceutical composition comprising ammonium in a pharmaceutically acceptable carrier, in amounts effective to preserve skeletal muscle.</p> |
