GENETIC ANALYSIS

摘要

This invention broadly relates to the field of molecular genetics. More specifically, the invention relates to methods for genetic analysis of DNA sequences corresponding to ancestral haplotypes of multigene complexes such as the Human Major Histocompatibility Complex and fragments thereof. The method in one embodiment comprises comparing a first DNA sequence corresponding to an ancestral haplotype or recombinant thereof of a multigene complex, such as the MHC, with one or more reference DNA sequences each corresponding to a separate ancestral haplotype so as to establish identity or non-identity therebetween and thus an assignment of ancestral haplotype of said first DNA sequence.