发明名称 |
Reverse micelles for delivery of nucleic acids |
摘要 |
A complex is described for delivery to a cell comprising inserting a nucleic acid into a reverse micelle. The reverse micelle has the property to compact the nucleic acid for easier delivery. Other molecules are used to interact with the nucleic acid-micelle complex to further enhance delivery such as a surfactant having a disulfide bond.
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申请公布号 |
US6429200(B1) |
申请公布日期 |
2002.08.06 |
申请号 |
US19990354957 |
申请日期 |
1999.07.16 |
申请人 |
MIRUS CORPORATION |
发明人 |
MONAHAN SEAN D.;WOLFF JON A.;SLATTUM PAUL M.;HAGSTROM JAMES E.;BUDKER VLADIMIR G. |
分类号 |
A61K9/107;A61K48/00;(IPC1-7):A61K31/710;A61K9/127;A61K31/711 |
主分类号 |
A61K9/107 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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