发明名称 TNF inhibitors for the treatment of retinal disorders
摘要 A method is disclosed for inhibiting the action of TNF for treating conditions of the optic nerve or retina in a human by administering a TNF antagonist for reducing the inflammation of neuronal tissue, or for modulating the immune response affecting neuronal tissue of a human by administering to the human a therapeutically effective dosage level of a TNF antagonist. The TNF antagonist is selected from the group consisting of etanercept, infliximab, pegylated soluble TNF receptor Type I (PEGsTNF-R1), CDP571 (a humanized monoclonal anti-TNF-alpha antibody), and D2E7 (a human anti-TNF mAb) for reducing the inflammation of neuronal tissue of a human, or for modulating the immune response affecting neuronal tissue of a human.
申请公布号 US6428787(B1) 申请公布日期 2002.08.06
申请号 US20000665529 申请日期 2000.09.19
申请人 TOBINICK EDWARD L. 发明人 TOBINICK EDWARD L.
分类号 A61K39/395;A61K39/40;A61K39/42;A61P25/00;A61P29/00;C07K16/24;(IPC1-7):A61K39/395 主分类号 A61K39/395
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