| 发明名称 |
SUSTAINED RELEASE PHARMACEUTICAL DOSAGE FORMS WITH MINIMIZEDPH DEPENDENT DISSOLUTION PROFILES |
| 摘要 |
A pharmaceutical composition comprising at least one pharmaceutically active agent that is pH dependent, at least one non-pH dependent sustained release agent, and at least one pH dependent agent that increases the dissolution rate of the at least one pharmaceutically active agent at a pH in excess of 5.5. Such compositions have minimized pH-dependent dissolution profiles or pH- independent dissolution profiles.
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| 申请公布号 |
CA2432178(A1) |
申请公布日期 |
2002.08.01 |
| 申请号 |
CA20012432178 |
申请日期 |
2001.12.20 |
| 申请人 |
SHIRE LABORATORIES, INC. |
发明人 |
CHANG, RONG-KUN;BURNSIDE, BETH;GUO, XIAODI |
| 分类号 |
A61K9/20;A61K9/22;A61K31/138;A61K31/155;A61K31/407;A61K31/4168;A61K31/4375;A61K31/4402;A61K31/519;A61K31/554;A61K31/7048;A61K45/08;A61K47/02;A61K47/10;A61K47/12;A61K47/32;A61K47/34;A61K47/36;A61K47/38;A61K47/44;A61P7/00;A61P25/28;A61P35/02;(IPC1-7):A61K9/22 |
主分类号 |
A61K9/20 |
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