发明名称 |
Stable pharmaceutical form of administration for peptides, proteins and nucleic acids |
摘要 |
The invention concerns storage-stable lyophilized pharmaceutical preparations of biomolecules wherein the biomolecules are selected from the group comprising proteins, peptides, nucleic acids and carbohydrates and additionally contain one or several basic D or L-amino acids in addition to one or several aminodicarboxylic acids, hydroxycarboxylic acids or dicarboxylic acids or physiologically compatible salts thereof. The auxiliary substances are present in the lyophilisate in a completely or partially amorphous form.
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申请公布号 |
US2002103126(A1) |
申请公布日期 |
2002.08.01 |
申请号 |
US20020046311 |
申请日期 |
2002.01.16 |
申请人 |
ROCHE DIAGNOSTICS GMBH |
发明人 |
RODEL WOLFGANG;MATTERN MARKUS;WINTER GERHARD |
分类号 |
A61K38/18;A61K38/19;A61K38/22;(IPC1-7):A61K48/00;A61K38/00;A61K31/715 |
主分类号 |
A61K38/18 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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