Oligo- oder Polyalkylengekoppelte Thrombininhibitoren

摘要

The invention relates to novel, covalent oligo and polyalkylene glycol conjugates containing synthetic inhibitors of trypsin-type serine protease, in particular inhibitors of the haemocoagulation protease thrombin. The invention also relates to synthetic intermediate stages required in the production of said conjugates and to the use of the latter for producing active agents for the treatment or prophylaxis of thrombotic complications.