发明名称 |
Automated identification of peptides |
摘要 |
A fully automated, user-independent method is described for computer-mediated interpretation of data derived by mass spectrometry of an experimental peptide to identify and characterize a corresponding peptide sequence in a peptide database. The method identifies the corresponding sequence if it is present in the database, without the need for a skilled observer to choose from amongst a list of possible matches. By using an automated back-read process, the present method can uniquely identify a corresponding peptide sequence in a database based on a single matching peptide sequence. The method also permits mapping of mass spectral data to sequences in peptide or nucleotide databases for unambiguous identification of exons; determining a correct reading frame; identifying artefacts and errors in sequences; identifying mutations and polymorphisms; identifying post-translational modifications; and identifying exon-intron boundaries.
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申请公布号 |
US2002102610(A1) |
申请公布日期 |
2002.08.01 |
申请号 |
US20010950313 |
申请日期 |
2001.09.10 |
申请人 |
TOWNSEND ROBERT REID;ROBINSON ANDREW WILLIAM |
发明人 |
TOWNSEND ROBERT REID;ROBINSON ANDREW WILLIAM |
分类号 |
G01N33/68;G06F19/00;G06K9/00;(IPC1-7):G06F19/00;G01V7/00;G01N33/53;G01N33/48 |
主分类号 |
G01N33/68 |
代理机构 |
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