METHODS FOR IDENTIFYING COMPOUNDS THAT MODULATE DISORDERS RELATED TO NITRIC OXIDE/CGMP-DEPENDENT PROTEIN KINASE SIGNALING

摘要

The invention provides a method of identifying a compound that modulates a disease associated with a nitric oxide/cGMP-dependent protein kinase network in a mammal. The method consists of (a) ad ministering a test compound to an invertebrate; and (b) measuring a foraging behavior of the invertebrate, wherein a compound that modulates the foraging behavior of the invertebrate is characterized as a compound that modulates a disease associated with a nitric oxide/cGMP-dependent protein kinase network in a mammal.