| 摘要 |
<p>The invention features Ikaros transcriptional control regions which include one or more Ikaros regulatory elements. Such regulatory regions can be used, for example, to direct expression of a sequence functionally unrelated to the Ikaros gene, e.g., a sequence encoding a reporter molecule. The invention further features a transgenic animal having an Ikaros transgene which includes an Ikaros transcriptional control region and a sequence functionally unrelated to Ikaros, e.g., a sequence encoding a reporter molecule, and methods of using such transgenic animals to evaluate hematopoietic development of an immune system component.</p> |
