发明名称 Kappa agonist compounds, pharmaceutical formulations and method of prevention and treatment of pruritus therewith
摘要 Method for the prevention or treatment of pruritus with anti-pruritic compounds is provided. The compounds of formulae I, II, IIA, III, IIIA, IV and IVA have the structure: wherein R1, R2, R3, R4; and X, X4, X5, X7, X9; Y, Z and n are as described in the specification.
申请公布号 US2002103164(A1) 申请公布日期 2002.08.01
申请号 US20010803976 申请日期 2001.03.13
申请人 ZHANG WEI YUAN;MAYCOCK ALAN L.;MARELLA ANTHONY MICHAEL;KUMAR VIRENDRA;GAUL FORREST;GUO DEQI 发明人 ZHANG WEI YUAN;MAYCOCK ALAN L.;MARELLA ANTHONY MICHAEL;KUMAR VIRENDRA;GAUL FORREST;GUO DEQI
分类号 A61K31/404;A61K31/4439;A61K45/06;C07D207/12;C07D209/42;C07D213/56;C07D241/04;C07D295/073;C07D403/06;(IPC1-7):A61K31/675;A61K31/495 主分类号 A61K31/404
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