| 发明名称 |
Glucagon-like insulinotropic peptide analogs, compositions, and methods of use |
| 摘要 |
<p>Glucagon-like insulinotropic peptide (GLP-1(7-37)) analogs and derivatives are disclosed. The analogs include amino acid substitutions, amino and carboxyl terminal modifications, and C6-C10 acylations. The claimed compounds stimulate the secretion or biosynthesis of insulin in poorly functioning beta cells and are therefore useful in treating Type II diabetics</p> |
| 申请公布号 |
EP1227151(A1) |
申请公布日期 |
2002.07.31 |
| 申请号 |
EP20020000257 |
申请日期 |
1995.10.13 |
| 申请人 |
ELI LILLY AND COMPANY |
发明人 |
CHEN, VICTOR JOHN;DIMARCHI, RICHARD DENNIS;KRIAUCIUNAS, AIDAS VLADAS;SMILEY, DAVID LEE;STUCKY, RUSSELL DEAN |
| 分类号 |
A61K38/26;A61K38/00;A61P3/08;A61P3/10;C07K14/575;C07K14/605;C12N15/16;(IPC1-7):C12N15/16 |
主分类号 |
A61K38/26 |
| 代理机构 |
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