发明名称 |
Particle formation methods and their products |
摘要 |
Embodiments of the invention provide a composition of a particulate coformulation which includes particles containing an active substance and an additive, wherein each particle contains a relative additive concentration increasing radially outwards from a particle center to a particle surface along a finite gradient. In one example, the particle surface is an additive-rich surface without a distinct physical boundary between the particle center and the particle surface. The relative additive concentration may have a continuous rate of change across the finite gradient. In some examples, an active substance:additive ratio of the particle surface is sufficiently low to form a protective surface layer around the active substance. Generally, the particle surface is free of the active substance. |
申请公布号 |
GB2371501(A) |
申请公布日期 |
2002.07.31 |
申请号 |
GB20010026193 |
申请日期 |
2001.11.01 |
申请人 |
* BRADFORD PARTICLE DESIGN LIMITED |
发明人 |
MAZEN HERMIZ * HANNA;PETER * YORK |
分类号 |
A23L1/00;A23L1/015;A61J3/02;A61K9/16;A61K9/50;A61K9/52;A61K31/49;A61K47/30;A61P33/06;B01J3/00;B01J19/00 |
主分类号 |
A23L1/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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