| 摘要 |
PROBLEM TO BE SOLVED: To obtain a new anilide derivative or a salt thereof having excellent microsomal triglyceride transfer protein-(MTP) inhibiting actions, etc., and useful as a medicine for prophylaxis and therapy of hyperlipidemia and/or arteriosclerosis, etc. SOLUTION: The anilide derivative represented by general formula (1) [wherein, R1 is an alkoxy, an alkylthio or the like; R2 is an alkoxy, an alkylthio or the like or forms a bicyclic or a tricyclic condensed hydrocarbon or condensed heterocycle together with the neighboring ring by combining with R6; R3 is H or the like; R4 is an alkyl, a cycloalkyl or the like; A is N or CR6 (R6 is H or forms the condensed rings by combining with R2); B is N, CH or the like; W is an aryl or the like; D is O or the like; E ring is an aromatic hydrocarbon or the like; G is a group represented by formula (a) or the like; X is O, single bond or the like; Y is an alkylene, an aryl, a heteroaryl or the like; Z is single bond, an alkylene or the like; and R5 is H, an alkyl or the like] or the salt thereof and the medicine containing the compound as an active ingredient are provided.
|
