| 发明名称 |
1-(2-OXO-ACETYL)PIPERIDINE-2-CARBOXYLIC ACID DERIVATIVES, PROCESS FOR PREPARING THE SAME, PHARMACEUTICAL COMPOSITION CONTAINING THEM AND METHOD OF TREATMENT |
| 摘要 |
The invention relates to 1-(2-oxo-acetyl)-piperidine-2-carboxylic acid derivatives of the formula (I): which maintain, increase or restore the cell sensitivity to therapeutic or prophylactic agents. The invention also relates to the pharmaceutical compositions containing said compounds and to methods for treating and preventing the development of multi-drug resistance. |
| 申请公布号 |
RO117791(B1) |
申请公布日期 |
2002.07.30 |
| 申请号 |
RO19950000599 |
申请日期 |
1993.09.27 |
| 申请人 |
VERTEX PHARMACEUTICALS INCORPORATED, CAMBRIDGE |
发明人 |
ARMISTEAD DAVID M;SAUNDERS JEFFREY O;BOGER JOSHUA S |
| 分类号 |
C07D211/60;A61K31/38;A61K31/395;A61K31/40;A61K31/4025;A61K31/4427;A61K31/4433;A61K31/445;A61K31/452;A61K31/4523;A61K31/52;A61P35/00;C07D207/16;C07D235/00;C07D239/00;C07D401/12;C07D401/14;C07D403/12;C07D405/14;C07D409/12;C07D471/04;C07D473/00;C07D487/04;(IPC1-7):C07D211/60 |
主分类号 |
C07D211/60 |
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